Inhibition of peptic activity by carbenoxolone and glycyrrhetinic acid

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Inhibition of peptic activity by carbenoxolone and glycyrrhetinic acid.

Carbenoxolone (Biogastrone, Berk) has been shown to reduce the peptic activity and total acidity of gastric juice obtained from anaesthetized pylorus-ligated rats without affecting significantly the volume of gastric juice secreted or the K(+) concentration. Glycyrrhetinic acid was less potent in reducing peptic activity and caused no reduction in total acidity. Antipeptic activity of carbenoxo...

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Preparation and Antibacterial Activity Evaluation of 18-β-glycyrrhetinic Acid Loaded PLGA Nanoparticles

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Synthesis and Pro-Apoptotic Activity of Novel Glycyrrhetinic Acid Derivatives

Triterpenoids are used for medicinal purposes in many countries. Some, such as oleanolic and glycyrrhetinic acids, are known to be anti-inflammatory and anticarcinogenic. However, the biological activities of these naturally occurring molecules against their particular targets are weak, so the synthesis of new synthetic analogues with enhanced potency is needed. By combining modifications to bo...

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ژورنال

عنوان ژورنال: Gut

سال: 1970

ISSN: 0017-5749

DOI: 10.1136/gut.11.4.344